Gaps in Expression

Gaps in Expression

Not expression in terms of emotional feeling manifestation, but gene expression.  I am talking about the fields of epigenetics and sociogenomics and how they enhance our understanding of the effects of environmental factors, like living in poverty, on humans at the cellular level, and the role that genetics play in behavior and social outcomes.

One of my favorite authors on this subject is NYU Professor Dalton Conley. Conley is particularly good at making confusing scientific research seem somewhat understandable to the average non-MD/PhD.  (Also, if you are a parent in need of a good dose of humor with how-to-screw-up-your-kids information, I highly recommend Conley’s Parentology: Everything You Wanted to Know about the Science of Raising Children but Were Too Exhausted to Ask and the equally amusing but less scientific, Babyhood by actor/comedian Paul Reiser.)

Whether your experience with the term “epigenetics” amounts to the sultry utterances by Ali Pfefferman (played by Gaby Hoffmann) in the hit series “Transparent”, or you are a leading sociogenomicist, check out our Topics section on Prenatal matters.  Learn more about the kinds of gaps that can manifest throughout the life of a child who was born to a mother who has lived in poverty.

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Resources

Epidemiology & Genomics Research Program | EGRP/DCCPS/NCI/NIH. (n.d.). National Cancer Institute | Division of Cancer Control & Population Studies. Retrieved October 24, 2016, from https://epi.grants.cancer.gov/
Spain, S. M., & Harms, P. D. (2014). A sociogenomic perspective on neuroscience in organizational behavior. Frontiers in Human Neuroscience, 8, 84. https://doi.org/10.3389/fnhum.2014.00084
Early Head Start University Partnership Grants: Buffering Children from Toxic Stress, 2011-2016. (n.d.). Office of Planning, Research & Evaluation | ACF. Retrieved October 24, 2016, from https://www.acf.hhs.gov/opre/research/project/early-head-start-university-partnership-grants-buffering-children-from
Skinner, M. K. (2015). Environmental Epigenetics and a Unified Theory of the Molecular Aspects of Evolution: A Neo-Lamarckian Concept that Facilitates Neo-Darwinian Evolution. Genome Biology and Evolution, 7(5), 1296–1302. https://doi.org/10.1093/gbe/evv073
Skinner, M. K. (2014). A New Kind of Inheritance. Scientific American, 311(2), 44–51. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330966/
Kundakovic, M. (2013). Prenatal Programming of Psychopathology: The Role of Epigenetic Mechanisms / PRENATALNO PROGRAMIRANJE PSIHIJATRIJSKIH POREMEĆAJA: ULOGA EPIGENETSKIH MEHANIZAMA. Journal of Medical Biochemistry, 32(4). https://doi.org/10.2478/jomb-2013-0047
Jirtle, R. L. (2012, April 18). Epigenetics: How Genes and Environment Interact (video cast). https://videocast.nih.gov/summary.asp?Live=10520&bhcp=1
Furrow, R. E., & Feldman, M. W. (2014). GENETIC VARIATION AND THE EVOLUTION OF EPIGENETIC REGULATION: SPECIAL SECTION. Evolution, 68(3), 673–683. https://doi.org/10.1111/evo.12225
Domingue, B. W., Belsky, D. W., Conley, D., Harris, K. M., & Boardman, J. D. (2015). Polygenic influence on educational attainment. AERA Open, 1(3), 2332858415599972. https://journals.sagepub.com/doi/abs/10.1177/2332858415599972?full=
Conley, Dalton | Sociology | New York University. (n.d.). Retrieved July 5, 2016, from http://sociology.as.nyu.edu/object/daltonconley.html
National Scientific Council on the Developing Child. (2012). The Science of Neglect-The Persistent Absence of Responsive Care Disrupts the Developing Brain (Working Paper No. 12). Harvard University. http://46y5eh11fhgw3ve3ytpwxt9r.wpengine.netdna-cdn.com/wp-content/uploads/2012/05/The-Science-of-Neglect-The-Persistent-Absence-of-Responsive-Care-Disrupts-the-Developing-Brain.pdf
Toxic Stress and the Development of Young Children. (2014). [Program Results Report]. Robert Wood Johnson Foundation. http://www.rwjf.org/content/dam/farm/reports/program_results_reports/2014/rwjf410424
Toxic Stress and the Development of Young Children - Supporting the Frontiers of Innovation. (2014). Robert Wood Johnson Foundation. http://www.rwjf.org/content/dam/farm/reports/program_results_reports/2014/rwjf410424
Randy Jirtle :: Research. (n.d.). Retrieved October 24, 2016, from http://randyjirtle.com/research
González-Pardo, H., & others. (2013). Epigenetics and its implications for psychology. Psicothema, 25(1), 3–12. http://www.unioviedo.net/reunido/index.php/PST/article/view/9859
Weinhold, B. (2006). Epigenetics: The Science of Change. Environmental Health Perspectives, 114(3), A160–A167. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392256/
Hobcraft, J. (2012). Epigenetics and the social sciences: progress, prospects and pitfalls. ESRC International Grand Challenge Symposium, 25–26. https://www.researchgate.net/profile/John_Hobcraft/publication/268062670_Epigenetics_and_the_Social_Sciences_Progress_Prospects_and_Pitfalls/links/552507410cf2caf11bfcf6b7.pdf
Euesden, J., Lewis, C., & O’Reilly, P. (n.d.). PRSice: Polygenic Risk Score software. Retrieved July 19, 2016, from http://www.prsice.info/
Skinner Laboratory: Principal Investigator: Michael K. Skinner. (n.d.). Retrieved July 19, 2016, from http://skinner.wsu.edu/piskinner.html
Reinberg, Dr. Danny, NYU Med. (n.d.). Retrieved July 6, 2016, from http://www.med.nyu.edu/ReinbergLab/HTML/research.html
Allis, C. David, The Rockefeller University. (n.d.). Retrieved July 6, 2016, from http://www.rockefeller.edu/research/faculty/labheads/DavidAllis/#content
Center on the Developing Child at Harvard University. (n.d.). Center on the Developing Child at Harvard University. Retrieved July 15, 2016, from http://developingchild.harvard.edu/
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